• Colonoscopy every 1–2 years
• If a parent or sibling was diagnosed with colorectal cancer at a younger age, start colonoscopy 2–5 years before the age when their colon cancer was diagnosed.
• Otherwise:
  
• For people with MLH1 and MSH2 mutations, start colonoscopies at age 20-25.
• For people with MSH6 and PMS2 mutations, start colonoscopies at age 30-35.
• Depending on gene mutation, family history and sex, consider urinalysis every year starting at age 30-35
• Depending on gene mutation and family history, consider pancreatic cancer screening starting at age 50
• Consider physical exam every year beginning at age 25-30
• Consider annual prostate cancer screening begining at age 40 with PSA blood test
  

Talk with your doctor about ways to prevent cancers or find them early. These may include:

Your doctor can help you decide which steps to take, and at what age.

Gene-specific management information is available here in English and Spanish

• About MLH1 Gene Mutations | Acerca de las Mutaciones Genéticas en MLH1
• About MSH2 Gene Mutations | Acerca de las Mutaciones Genéticas en MSH2
• About MSH6 Gene Mutations | Acerca de las Mutaciones Genéticas en MSH6
• About PMS2 Mutations | Acerca de las Mutaciones Genéticas en PMS2