Skip Navigation LinksWhen to Refer to Genetic Counseling

  • Any MLH1, MSH2, MSH6, PMS2 mutation identified on tumor genomic profiling
  • Any reported germline incidental finding (Tempus)
  • When somatic findings and family history match a hereditary cancer syndrome
  • All MSI high tumors
  • Refer based on personal or family history indication regardless of somatic results
    • i.e. Early age of diagnosis (<50: colon, uterine)