Surveillance

• Colonoscopy with polypectomy beginning at age 20-25
• If a relative was diagnosed with colon cancer prior to age 25, begin colonoscopy 2-5 years prior to that relative's diagnosis.
• Repeat every 1-2 years
• Annual physical examination including neurologic examination beginning at age 25-30
• Consider EGD with extended duodenoscopy beginning at age 40 years
• Repeat every 3-5 years
• Consider annual dermatological exams
• Consider annual pancreas cancer imaging (alternating between EUS and MRI) if family history includes close relative(s) with pancreas cancer
• Begin at age 50 or 10 years earlier than the youngest diagnosis of pancreatic cancer in the family, whichever is earliest.
  
• Consider yearly urinalysis beginning at age 30-35
  
• Consider yearly prostate cancer screening begining at age 40 with PSA blood test

• Women: Consider prophylactic hysterectomy and bilateral salpingo-oophorectomy (removal of the uterus, ovaries, and fallopian tubes) when childbearing is complete.
• If not pursuing these risk-reducing surgeries:
• Be aware of and report dysfunctional uterine bleeding, abdominal or pelvic pain, bloating, difficulty eating, and/or increased urinary frequency or urgency if symptoms persist for several weeks
• Consider yearly endometrial sampling beginning at age 30-35, every 1-2 years
• Consider use of hormonal birth control for risk reduction
• Consider taking daily aspirin for colon cancer risk reduction
• Consider H.pylori testing and treating if detected

• Colonoscopy with polypectomy beginning at age 30-35
• If a relative was diagnosed with colon cancer prior to age 25, begin colonoscopy 2-5 years prior to that relative's diagnosis.
• Repeat every 1-2 years
• Annual physical examination including neurologic examination beginning at age 25-30
• Consider EGD with extended duodenoscopy beginning at age 40 years
• Repeat every 3-5 years
• Consider annual dermatological exams
• Consider annual pancreas cancer imaging (alternating between EUS and MRI) if family history includes close relative(s) with pancreas cancer
• Begin at age 50 or 10 years earlier than the youngest diagnosis of pancreatic cancer in the family, whichever is earliest.
• Consider yearly urinalysis beginning at age 30-35
• Consider yearly prostate cancer screening begining at age 40 with PSA blood test
  

• Women: Consider prophylactic hysterectomy and bilateral salpingo-oophorectomy (removal of the uterus, ovaries, and fallopian tubes) when childbearing is complete.
• If not pursuing these risk-reducing surgeries:
• Be aware of and report dysfunctional uterine bleeding, abdominal or pelvic pain, bloating, difficulty eating, and/or increased urinary frequency or urgency if symptoms persist for several weeks
• Consider yearly endometrial sampling beginning at age 30-35, every 1-2 years
• Consider use of hormonal birth control for risk reduction
• Consider taking daily aspirin for colon cancer risk reduction
• Consider H.pylori testing and treating if detected

Surveillance

• Colonoscopy with polypectomy beginning at age 30-35
• If a relative was diagnosed with colon cancer prior to age 25, begin colonoscopy 2-5 years prior to that relative's diagnosis.
• Repeat every 1-2 years
• Annual physical examination including neurologic examination beginning at age 25-30
• Consider EGD with extended duodenoscopy beginning at age 40 years
• Repeat every 3-5 years
• Consider annual dermatological exams
• Consider yearly urinalysis beginning at age 30-35
• Consider yearly prostate cancer screening begining at age 40 with PSA blood test
  

• Women: Consider prophylactic hysterectomy and bilateral salpingo-oophorectomy (BSO: removal of the uterus, ovaries, and fallopian tubes) when childbearing is complete. Notably, there is insufficient evidence to support the utility of BSO.
• If not pursuing these risk-reducing surgeries:
• Be aware of and report dysfunctional uterine bleeding, abdominal or pelvic pain, bloating, difficulty eating, and/or increased urinary frequency or urgency if symptoms persist for several weeks
• Consider yearly endometrial sampling beginning at age 30-35, every 1-2 years
• Consider use of hormonal birth control for risk reduction
• Consider taking daily aspirin for colon cancer risk reduction
• Consider H.pylori testing and treating if detected