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Clinicians are encouraged to refer patients for genetic counseling for evaluation of Lynch syndrome when the patient meets any of the following criteria:

The patient has a biological relative known to have Lynch syndrome.

The patient has a personal history of a dMMR tumor diagnosed at any age.

The patient has either colorectal or endometrial cancer AND any of the following:

  • Their diagnosis was <50 years old.
  • They have a history of a synchronous or metachronous Lynch-related cancer.
  • They have a first- or second-degree relative with a Lynch-related cancer diagnosed <50 years old (e.g. parents, sibling, child, aunt, uncle, grandparent, grandchild)
  • The have two or more first- or second-degree relatives with a Lynch-related cancer at any age.
  • They have one or more first- or second-degree relatives with colorectal or endometrial cancer diagnosed <50 years old.
  • They have one or more first- or second-degree relatives with a colorectal or endometrial cancer and a synchronous or metachronous Lynch-related cancer at any age.
  • They have two or more first- or second-degree relatives with a Lynch-related cancer, including one diagnosed <50 years old.
  • They have three of more first- or second-degree relatives with Lynch-related cancers at any age.

If you do not have a genetics services at your hospital, you can use the following website to find a local genetic counselor for your patient by entering the patient's zip code into the search engine and selecting "cancer" from the list of specialties: LINK

If your patient would like to be seen at the Huntsman Cancer Institute's Family Cancer Assessment Clinic for either a genetic counseling appointment or long-term follow-up in the High Risk GI Cancer Clinic, they can find more information about our services here: FCAC Homepage

Presenter: Ambreen Khan, CGC 
Talk: Identifying families with Lynch syndrome